Chronic Leg Ulceration ?Connective Tissue Defect

Ultrasound therapy in chronic leg ulceration: a meta-analysis.

We reviewed all articles on ultrasound therapy published since 1950 to assess the evidence for an effect of this therapy in the treatment of chronic leg ulcers. Fourteen studies concerning ultrasound therapy, chronic leg ulcers, and wound healing were found. The six studies that fulfilled inclusion criteria for a randomized controlled trial were generally found lacking with respect to descripti...

Chronic leg wounds and ulceration: an ongoing challenge.

Impact of exudate and odour from chronic venous leg ulceration.

AIMS To explore depression in people treated for chronic venous leg ulceration, and to assess the impact of excessive exudate, leading to leakage and odour, on their daily lives, overall health and quality of life. METHODS Completion of a questionnaire and Hospital Anxiety and Depression Scale to determine the prevalence of anxiety and depression in people with chronic leg ulceration (n = 196...

Venous Leg Ulceration

Venous leg ulcers are among the most common leg ulcerations. Advancing age, sex, race, phlebitis, family history, obesity, prolonged standing, and number of pregnancies are risk factors. Although the main pathogenetic mechanism is venous hypertension, leading to vein wall damage and thereby a cascade of events resulting in ulceration, there is no consensus about progression from venous hyperten...

Recalcitrant leg ulcer due to mixed connective tissue disease.

We present a 28-year-old woman with mixed connective tissue disease (MCTD) complicated by a recalcitrant longstanding leg ulcer, which responded to complex therapy with local polydine, systemic ciprofloxacin, iloprost, enoxaparin and aspirin. Cyclophosphamide pulse therapy and corticosteroids controlled the systemic inflammation but failed to heal the leg ulcer. We considered a rationale of com...